Antimicrobial Activity Of Oil-bearing Plants Lamiaceae Lindl. Towards Escherichia Coli

Abstract

L.A. Kotyuk

The paper relates to study of biological activity of 40% ethanol extracts of Dracocephalum moldavica, Hyssopus officinalis, Satureja hortensis, Lophanthus anisatus and Monarda diduma, grown in Ukrainian Polissya, against a pathogenic agent Escherichia coli UCM – B (ATCC 25922). The research proves that ethanol extracts of H. officinalis, D. moldavica, S. hortensis, L. anisatus exert antimicrobial activity as the extracted substances provided a twofold increase in minimum bactericidal concentration (MBC) values against E. coli. Likewise, a twofold increase was observed in minimum inhibitory concentration (MIC) of L. anisatus ethanol extracts. As to M. diduma ethanol extracts, their inhibitory and bactericidal influence on E. coli was not registered. Oil-bearing plants (family Lamiaceae), grown in Zhytomyr Polissya, are characterized by antimicrobial properties, attributed to biologically active substances that are formed and accumulated in the plant material. The main components of hyssop essential oil are isopinocamphone (44.43%), pinocamphone (35.49%), myrtenol (5.26 %), germacrene D (3.15 %), pulegone (2.93 %), bicyclogermacrene (1.35 %). In mint anise essential oil prevailed pulegone (59.19%), izomenton (14.34%), bicyclogermacrene (3,21 %), β-kariofilen (2,99 %), menton (2.21 %), 1,6-germacradien-5-ol (1.5 %), isopulegone (1.4 %), in summer savory – carvacrol (89.07%), g-terpinene (3.53%), α-thujone (1.7 %), camphor (1.48 %). The dominant components of moldavian dragonhead essential oil were geranial (26.19%) and neral (22.36%), 2-(1-hydroxy-1-isopropyl)-cyklopentanon (8.29 % ), 2,3-dehydro-1,8-cineole (6.87 %), 3-(1-hydroxy-1-isopropyl) cyklopentanon (6,51 %), nerol (4.74 %), 3-methyl-2-cyclohexane 1-on (2.13 %). The paper draws attention to further more detailed study of ethanol extracts of hyssop, moldavian dragonhead, summer savory, mint anise with the aim of producing antibacterial herbal preparations.

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