Y. Lesyk, A. Ivanytska, I. Kovalchuk, S. Monastyrska, N. Hoivanovych, B. Gutyj, M. Zhelavskyi, O. Hulai, S. Midyk, O. Yakubchak and T. Poltavchenko

The article presents the results of the study for the influence of the rabbits feeding with various amounts of citric acid (25, 50 and 75 μg Si kg-1 of body weight, I-III experimental groups) from 52 to 110 days of life of the rabbits, obtained by nanotechnology method and sodium metasilicate (2.5 and 5.0 mg Si kg-1 of body weight, IV–V experimental groups) on hematological parameters and total lipid content and their fractional composition in the blood and liver tissue. It was established that the number of erythrocytes in the blood of rabbits in II and III experimental groups was higher by 18.4 and 20.7% (P<0.05) at 31 days of study compared with control. At day 58 of the experiment, the total number of red blood cells in animals of the 1st, 2nd, and 3rd experimental groups was respectively higher by 14.9, 19.1, and 17.6% (P<0.05) than in the control. According to white blood indexes, the differences from control were found during the feeding of supplements with a significantly higher change of 30.9% (P<0.05) in 31 days in the blood of animals in the third experimental group. It was found that the feeding of silicic acid compounds did not significantly change the total lipids and phospholipids content, but led to the redistribution of their classes in the investigated tissues. Under the action of citrate silicon in the amount of 50 and 75 μg Si kg-1 of body weight, there was a decrease in the content of triacylglycerols in the blood plasma by 35 and 52% (P<0.05–0.01), respectively, compared with control. Investigation of the fractional lipids composition in the liver tissue showed a lower content of triacylglycerols and esterified cholesterol in animals of the II and III experimental groups compared with the control group. Consequently, the results of blood analyses and the fractional lipids composition in the individual tissues of the rabbit body indicate positive changes contributing to metabolic accumulation of energy and plastic components in the trophic chain and confirm the feasibility of adding citrate silicon in the rabbit diet, taking into account its physiologically substantiated amount.

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