Influence of the seasonal and compositional changes on 4,4-dichlorodiphenyltrichloroethane (DDT) contamination in cows milk
Abstract
V.M. Karaulna, L.V. Ezerkovska, I.D. Prymak, Y.V. Fedoruk, S.V. Chernyuk, L.M. Karpuk, A.A. Pavlichenko, S.A. Polishchuk, S.M. Kubrak, V.V. Bilkevich, N.M. Fedoruk
The article presents the results of investigations on the determination of the content of organochlorine pesticides and DDT in the milk samples obtained in some settlements (village Movchanivka, Leninske, Mali Lisivtsi, Velikopolovetskye, and Pustovarivka), Skvirsky district, Kyiv oblast. The analysis of fat and protein content in milk in the winter and summer periods of the year. We registered that in the winter period with an increase of fat content in the milk, the concentration of DDT and its derivatives also increases. The content of organochlorine compounds in cow's milk did not exceed the maximum permissible level. In case of prolonged inflow of pesticide residues with food products into the human organism or feed into the animal organism, toxic substances gradually accumulate in them and have a negative influence on different functional systems of organisms, causing disturbances in their work. Purification from harmful substances is carried out by metabolic conversion of toxicants into more mobile in tissues compounds that can be more easily removed from the body. The process of removal of harmful substances, including metabolites of pesticides from the body warm-blooded with biological fluids and fecal masses is very long, and its intensity is mostly due to the degree of toxic load of xenobiotics on a person or animal. An indicator of the degree and quality of toxic exposure of humans and domestic animals to pesticides that live in a particular agricultural region may be the levels of these pesticides in human and warm-blooded milk. However, the most convenient and affordable indicator of pesticide exposure to organisms may be found in cattle milk, primarily cow milk. The great advantage of this object of toxic load indication is the unlimited possibility of biomaterial selection and deficiency of volumes, necessary for sanitary and hygienic researches because herds of cattle are almost in every farm of different agricultural regions.
Keywords: pesticides, DDT (4,4’-dichlorodiphenyltrichloroethane), cattle, cow's milk, accumulation
References
Antonov, B.I. (1989). Laboratory research in veterinary medicine: Chemical and toxicological methods: Handbook. Moscow: Agropromizdat (in Russian).
Davidyuk, E.I. (1998) Ecological and hygienic assessment of agrobiocenosis pollution by some organochlorine pesticides. Actual problems of ecohygiene and toxicology: Proceed. Int. Sc. Conf. Kyiv, May 28–29, 79–82. (in Ukrainian).
Handbook of pesticides: Hygiene and toxicology (1986). A.V. Pavlov (Ed.). Kyiv, Urozhay (in Ukrainian).
Klisenko, M.A., Davidyuk, E.I., Demchenko, V.F. (1994) Detoxication of some organochlorine compounds in agroekocenosies and level of their effect on the rural population health, safety and ergonomic aspects in use of chemicals in agriculture and forestry. Kiyv (in Ukrainian).
Lunev, M.I. (1992) Pesticides and protection of agrophytocenoses. Moscow: Kolos (in Russian)
Milk and dairy products. (1991). Methods for fat determining. GOST 5867-90. Moscow: Izdatelstvo standartov. Interstate standard (in Russian).
Milk. (2009). Methods for determination of protein GOST 25179-90. Moscow: Standardinform. Interstate standard (in Russian).
Moklyachuk, L.I. (2008). Monitoring of persistent organochlorine pesticides in agriculture of the south of Ukraine. Collection of scientific works of the National Research Center “Institute of Agriculture of Ukrainian Agrarian Academy of Sciences”, 1, 65–70 (in Ukrainian)
Patika, V.P., Makarenko, N.A., Moklyachuk, L.I. (2005). Agroecological assessment of mineral fertilizers and pesticides. Kiyv (in Ukrainian)
State sanitary rules and norms. (2001). DsanPiN 8.8.1.2.3.4-000-2001. Permissible doses, concentrations, quantities and levels of pesticides in agricultural raw materials, food, air of the working area, atmospheric air, water of reservoirs, and soil. Kyiv (in Ukrainian).