Metabolism in replacement chickens at different ratios of arginine and lysine


I. Ibatullin, M. Kryvenok, I. Ilchuk, V. Mykhalska, A. Getja, S. Boyarchuk

The influence of different levels of arginine and lysine in compound feeds of replacement chickens on their growth, development and metabolism was studied. The effective ratio of arginine to lysine in the diets of replacement chickens was experimentally established, which, depending on the rearing period, was: 1.0:1 for 1-3 weeks, 1.1:1 for 4-8 weeks, 1.2:1 for  16 weeks and 1.2:1 for 17-18 weeks. It was found that the change in the ratio of arginine and lysine in poultry diets has a much higher degree of influence on their productivity, digestibility of feed nutrients, assimilation and efficiency of amino acids than changes in the levels of these amino acids. It was found that the ratio of arginine and lysine in the last period of rearing chickens (16-18 weeks) to a lesser extent affects the productivity of replacement young (R2=0.59) compared to the first (R2=0.96) and second periods of rearing (R2=0.65). The growth of replacement young during all periods of the experiment and the nature of the effect of changes in levels and ratios of these amino acids in feed depending on age and productivity, described by a mathematical model with nonlinear characteristics (polynomial trend line), which has a higher value of approximation (R2) linear dependence. The use of modern modeling methods and the proposed regression equations allow to predict the content of amino acids in feed for replacement young poultry in accordance with the program of their cultivation and amino acid composition of feed.

Keywords: Replacement young stock; Essential amino acids; Arginine; Lysine; Prediction; Regression equation


Al-Saffar, A.A., Rose, S.P. (2002). The response of laying hens to dietary amino acids. World's Poultry Science Journal.,58(5), 209–234.

Baker, D.H., Han, Y. (1994). Ideal amino acid profile for chicks during the first three weeks post-hatching. Poultry Science, 73(9),  14411447.

Balnave, D, Brake, J. (2002). Re-evaluation of the classical dietary arginine:lysine interaction for modern poultry diets: a review. Worlds Poult Sci J, 58, 275–289. doi: 10.1079 / WPS20020021.

Campos, A.M.A., Rostagno, H.S., Nogueira, E.T., Albino, L.F.T., Pereira, J.P.L., Maia, R.C. (2012). Atualização da proteína ideal para frangos de corte: arginina, isoleucina, valina e triptofano. Revista Brasileira de Zootecnia, 41(2), 326–332.

Carvalho, F.B. de, Stringhini, J.H., Matos, M.S., Café, M.B., Leandro, N.S.M.,… Jardim Filho, R.M. (2015). Egg quality of hens fed different digestible lysine and arginine levels. Brazilian Journal of Poultry Science17(1), 63-68.

Chamruspollert, M., Pesti, G.M.,  Bakalli, R.I. (2002). Dietary interrelationships among arginine, methionine, and lysine in young broiler chicks. British Journal of Nutrition, 88(6), 655–660 doi:

Cynober, L., Le Boucher, J., Vasson, M. P. (1995). Arginine metabolism in mammals. Journal of Nutritional Biochemistry, 6, 402–413.

Ebrahimi, M., Zare Shahneh, A., Shivazad, M., Ansari Pirsaraei, Z., Tebianian, M., Ruiz-Feria, C.A., Adibmoradi, M., Nourijelyani, K., Mohamadnejad, F. (2014). The effect of feeding excess arginine on lipogenic gene expression and growth performance in broilers. British Poultry Science, 55, 81-88.

Elliot, M.A. (2008). Amino acid nutrition of commercial pullets and layers. California Animal Nutrition Conference, May 21–22, Fresno, California. 139–165.

Ertechini, A.G. (2006). Nutrição de monogástricos. Lavras: UFLA

Fatufe, A., Timmler, R., Rodehutscord, M. (2004). Response to lysine intake in composition of body weight gain and efficiency of lysine utilization of growing male chickens from two genotypes. Poultry Science. 83, 8, 1314–1324.

Fouad, A.M., El-Senousey, H.K., Yang, X.J., Yao, J.H. (2012). Role of dietary L-arginine in poultry production. Int J Poult Sci. 11, 718–729. doi: 10.3923 / ijps.2012.718.729.

Guoyao, Wu. (2014). Dietary requirements of synthesizable amino acids by animals: a paradigm shift in protein nutrition. Journal of Animal Science and Biotechnology, 5(1), 34. doi: 10.1186/2049-1891-5-34

Jahanian, R., Khalifeh???Gholi, M. (2017). Marginal deficiencies of dietary arginine and methionine could suppress growth performance and immunological responses in broiler chickens. Journal of Animal Physiology and Animal Nutrition.

Kononenko, V.K., Ibatullin, I.I., Patrov, V.S. (2000). Praktykum z osnov naukovykh doslidzhen u tvarynnytstvi (in Ukrainian).

Kriukov, B., Bevziu, V., Polunyna, S. (1997). Vybor kormov s vysokym soderzhanyem proteyna. Ptytsevodstvo, 6, 17–18 (in Russian).

Kryvenok, M.Ia., Ilchuk, I.I. (2016). Teoretychne obgruntuvannia spivvidnoshennia metioninu i treoninu u ratsionakh remontnykh kurchat. Suchasne ptakhivnytstvo, 10-11, 6 (in Ukrainian).

Kryvenok, M.J., Ilchuk, I.I, Mykhalska, V.M. (2017). Prognosis of dietary glycine needs of replacement chicks. Ukrainian Journal of Ecology, 7(4), 46–50, doi: 10.15421/2017_85

Labadan, M.C.Jr., Hsu, K.N., Austic, R.E. (2001). Lysine and arginine requirements of broiler chickens at two- to three-week intervals to eight weeks of age. Poultry Science, 80(5), 599–606.

Lakyn, H.F. (1990). Byometryia. Moscow (in Russian).

Lemme, A. (2009). Amino acid recommendations for laying hens. Lohmann Information, 44(2), 21-32.

Sklan, D., Noy, Y. (2003). Crude protein and essential amino acid requirements in chicks during the first week posthatch. British Poultry Science. 44, 2, 266–274.

De Souza Reis, R., de Toledo Barreto, S.L.,  da Silva Abjaude, W., Dutra, D.R., Santos, M., de Paula, E. (2012). Relationship of arginine with lysine in diets for laying Japanese quails. Revista Brasileira de Zootecnia. 41, 1.

Urdaneta-Rincon M., Leeson S. (2004). Effect of dietary crude protein and b lysine on feather growth in chicks to twentyone days of age. Poultry Science, 83(10), 1713–1717.

Wecke, C., Pastor, A., Liebert, F. (2016). Validation of the Lysine Requirement as Reference Amino Acid for Ideal In-Feed Amino Acid Ratios in Modern Fast Growing Meat-Type Chickens  DOI: 10.4236/ojas.2016.63024

Zampiga, M., Laghi, L., Petracci, M., Zhu, Ch., Meluzzi, A., Dridi, S., Sirri, F. (2018). Effect of dietary arginine to lysine ratios on productive performance, meat quality, plasma and muscle metabolomics profile in fast-growing broiler chickens. Journal of Animal Science and Biotechnology, 9, 79. doi: 10.1186/s40104-018-0294-5

Share this article