Morphological changes in sheep organs caused by Bunostomum trigonocephalum infestation


O.M. Shchebentovska, M.V. Golubtsova, M.M. Danko, M.V. Zakrevska, A.K. Kostynyuk, G.A. Zon, L. B. Ivanovskaya, L. N. Lazorenko, J.V. Negreba, V.I. Risovaniy

Strongylatoses are the most common diseases of the ungulates globally and in Ukraine, caused by extremely pathogenic helminths that provoke diseases with noticeable clinical signs and high mortality rate. The humid climate of Western Ukraine's mountainous regions, the lack of veterinary specialists in the highlands, and the resistance of larval forms and helminth eggs to the environmental conditions contribute to the spread of strongyles among sheep. In sheep invasion by the Bunostomum trigonocephalum nematode, the main clinical manifestations were characterized by depression, tachycardia, tachypnea, anemia, cachexia, and recurrent diarrhea. The following signs represent characteristic pathological changes: edema of subcutaneous tissue in the neck and chest area, anemia of the mucous membranes, congestive hyperemia and pulmonary edema, serous lymphadenitis and hydropericarditis, dystrophic changes in the liver and kidney, and catarrhal enteritis. Histologically, an inflammatory reaction and edema with thickening of the interstitial lung tissue in the areas of mass accumulation of Bunostomum trigonocephalum larvae and cellular infiltration were discovered in the alveoli and bronchi. Edema of the mucous membrane plate was detected in the jejunum and the proliferation of lymphocytes, histiocytes, plasma cells and macrophages, dystrophic and necrobiotic changes in endocrinocytes with pyknosis and lysis of the nuclei. Circulatory disorders with dystrophy and diffuse necrosis of hepatocytes were found in the liver, and hyaline-drop dystrophy of the nephrothelium of the nephron cortical tubules was found in the kidney.

Keywords: Bunostomum trigonocephalum; clinical signs; pathological changes; pneumonia; parenchymal hepatitis; proliferation; delimphatization


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