Oxidant/Antioxidant Balance in Cows and Sheep in Antenatal Pathology

Abstract

P. Sklyarov, S. Fedorenko, S. Naumenko, P. Antonenko, V. Zazharskyi, R. Mylostyvyi, N. Zazharska

It has been established that antenatal pathology causes changes in the oxidant/antioxidant balance indices of cows within the range from 24.3% to 41.5%, and in sheep - 17.2-26.2%. In particular, in cows the content of serum catalase decreased by 29.9% and that of superoxide dismutase - by 29.1%, in erythrocytes, catalase - by 35.7%, and reduced glutathione - by 28.0%, and by hemoglobin by 24.3%, the number of red blood cells - by 28.7% and the concentration of 2,3-diphosphoglycerate - by 41.5%. At the same time, the content of malondialdehyde in serum and erythrocytes, on the contrary, increased by 32.4% and 32.5%, respectively, and there was a change in oxidant/antioxidant balance from 1 : 1 to 1 : 3 conventional units. In sheep, the content of serum catalase decreased by 17.2% and that of superoxide dismutase - by 21.6%, in erythrocytes catalase - by 23.9% and in reduced glutathione - by 21.1%, hemoglobin content decreased by 26.2%, the number of erythrocytes - by 24,1% and the concentration of 2,3-diphosphoglycerate - by 21.2%. While the content of malondialdehyde in blood serum and in erythrocytes, on the contrary, increased by 23.7% and 22.3%, respectively, and the change in oxidant/antioxidant balance occurred from 2:1 to 1:3 conventional units.

Keywords: Cows; Sheep; Antenatal pathology; Oxidant/Antioxidant balance
 

References

Al-Qudah, K. M. (2011). Oxidant and antioxidant profile of hyperketonemic ewes affected by pregnancy toxemia. Veterinary Clinical Pathology, 40(1), 60–65.

Chavatte-Palmer, P., Lee, R., Bertolini, M., Jammes, H., Schmidt, M., & Callesen, H. (2014). Pregnancy and Neonatal Care of SCNT Animals. Principles of Cloning, 107–126.

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